High Containment Systems: From SafePort to SafePort Evo

One goal, two high-containment solutions

Both the SafePort and SafePort Evo are designed for high-containment powder transfer up to OEB 5. However, their design and application focus differ.

The established SafePort uses a DN150 interface and was developed particularly for larger product volumes. TransferBag sizes range from small quantities up to 180 litres, making the system especially suitable for larger batch sizes and processes requiring a large transfer area.

Its robust connection concept has proven itself in demanding high-containment applications. Up to 20 TransferBags can be docked during one process sequence, while an optional cleaning system supports cleaning at the end of the process.

The SafePort Evo represents the next generation of the concept. Designed around a 4-inch connection with a 6-inch process area, it focuses on compactness, intuitive operation and process efficiency. TransferBag volumes from 5 to 40 litres are available, making the system particularly suitable for smaller and frequently changing product quantities.

Most importantly, the Evo concept enables unlimited docking cycles.

Moving way from the tower design

One of the most visible differences between the two systems is their construction.

With the established SafePort, consecutive docking operations result in a tower-type configuration. This concept works particularly well where larger product quantities need to be transferred through a DN150 interface.

SafePort Evo eliminates this tower design. Its system height remains constant throughout the process, regardless of the number of docking cycles.

This creates a more compact setup and can simplify integration into production equipment, isolators and other areas where available space and ergonomics are important considerations.

Simplified docking and intuitive handling

High containment should not come at the expense of usability.

SafePort Evo was therefore designed to reduce the number of operating steps required during the transfer process. An integrated position indicator provides clear visual feedback during docking: the TransferBag is connected with a turning movement until the indicator shows the correct position.

The remaining bag section can then be removed, the SafeStick opened and the system is ready for product transfer.

Fewer handling steps not only make the process faster and more intuitive, but can also help reduce the potential for operator errors during repetitive transfer operations.

Free product flow without a split valve

Both SafePort concepts provide an unobstructed transfer path without a flap. With SafePort Evo, this principle has been incorporated into an even more compact connection concept.

No split valve is required, allowing the powder to flow freely through the transfer area. This helps minimise product losses and supports high product yield, particularly important when working with valuable APIs and HPAPIs.

At the same time, eliminating a split valve reduces the complexity and investment associated with conventional high-containment transfer technology.

Integrated cleaning and double containment

SafePort Evo also introduces additional functionality for demanding production environments.

A WIP connection for the spray ring is integrated into the connection head, providing an integrated approach to cleaning. With the established SafePort, a cleaning system is available as an optional solution.

For applications requiring an additional level of protection, SafePort Evo can also be used for double-containment applications up to OEB 6, for example when integrated into an isolator.

This makes the system particularly interesting for processes involving highly potent substances and environments where multiple containment barriers are required.

SafePort or SafePort Evo?

The introduction of SafePort Evo does not simply mean replacing one system with another. The two solutions address different process requirements.

SafePort remains particularly suitable when larger product quantities need to be transferred and a robust DN150 connection with capacities of up to 180 litres is required.

SafePort Evo is designed for processes where compact dimensions, smaller product quantities, frequent product changes and repeated docking operations are priorities. Its constant system height, unlimited docking cycles, integrated position indicator and reduced number of handling steps make it especially suitable for flexible pharmaceutical production environments.

Both systems provide OEB 5 containment and can be configured with different film materials according to process requirements.

SafePort vs SafePort Evo

The evolution of high-containment transfer

As pharmaceutical manufacturing moves towards increasingly potent products, smaller batch sizes and more flexible production concepts, containment technology has to evolve accordingly.

SafePort Evo builds on the established principles of the SafePort system while addressing these changing requirements. The result is a compact high-containment transfer solution combining operator protection with intuitive handling, efficient product flow and greater process flexibility.

Whether the process requires the larger capacity of SafePort or the compact, flexible architecture of SafePort Evo, the objective remains the same: safe, efficient and reliable product transfer in high-containment environments.

Discover the Lugaia TransferBag Systems

Learn more about SafePort, SafePort Evo and our flexible TransferBag solutions for pharmaceutical, biotech and high-containment applications.

Find the right containment solution for your process together with us.